{"id":239,"date":"2025-05-30T16:22:29","date_gmt":"2025-05-30T08:22:29","guid":{"rendered":"https:\/\/www.bihec.com\/diantpharma\/?p=239"},"modified":"2025-05-30T16:22:29","modified_gmt":"2025-05-30T08:22:29","slug":"%e7%be%8e%e5%9b%bddiant-laru%e7%ba%b3%e7%b1%b3%e9%a2%97%e7%b2%92%e5%88%b6%e5%a4%87%e7%b3%bb%e7%bb%9f","status":"publish","type":"post","link":"https:\/\/www.bihec.com\/diantpharma\/%e7%be%8e%e5%9b%bddiant-laru%e7%ba%b3%e7%b1%b3%e9%a2%97%e7%b2%92%e5%88%b6%e5%a4%87%e7%b3%bb%e7%bb%9f\/","title":{"rendered":"\u7f8e\u56fdDIANT Laru\u7eb3\u7c73\u9897\u7c92\u5236\u5907\u7cfb\u7edf, mRNA\u75ab\u82d7\u8102\u8d28\u7eb3\u7c73\u7c92\u5236\u5907\u7cfb\u7edf, mRNA\u836f\u7269\/\u6838\u9178\u836f\u7269\u9012\u9001\u7cfb\u7edf"},"content":{"rendered":"<p><strong>\u7f8e\u56fdDIANT Laru<a href=\"https:\/\/www.bihec.com\/diantpharma\/tag\/%e7%ba%b3%e7%b1%b3%e9%a2%97%e7%b2%92%e5%88%b6%e5%a4%87%e7%b3%bb%e7%bb%9f\/\" title=\"View all posts in \u7eb3\u7c73\u9897\u7c92\u5236\u5907\u7cfb\u7edf\" target=\"_blank\">\u7eb3\u7c73\u9897\u7c92\u5236\u5907\u7cfb\u7edf<\/a>, <a href=\"https:\/\/www.bihec.com\/diantpharma\/tag\/mrna%e7%96%ab%e8%8b%97%e8%84%82%e8%b4%a8%e7%ba%b3%e7%b1%b3%e7%b2%92%e5%88%b6%e5%a4%87%e7%b3%bb%e7%bb%9f\/\" title=\"View all posts in mRNA\u75ab\u82d7\u8102\u8d28\u7eb3\u7c73\u7c92\u5236\u5907\u7cfb\u7edf\" target=\"_blank\">mRNA\u75ab\u82d7\u8102\u8d28\u7eb3\u7c73\u7c92\u5236\u5907\u7cfb\u7edf<\/a>, mRNA\u836f\u7269\/<a href=\"https:\/\/www.bihec.com\/diantpharma\/tag\/%e6%a0%b8%e9%85%b8%e8%8d%af%e7%89%a9%e9%80%92%e9%80%81%e7%b3%bb%e7%bb%9f\/\" title=\"View all posts in \u6838\u9178\u836f\u7269\u9012\u9001\u7cfb\u7edf\" target=\"_blank\">\u6838\u9178\u836f\u7269\u9012\u9001\u7cfb\u7edf<\/a><\/strong><\/p>\n<p>\u968f\u7740\u57fa\u4e8e\u7eb3\u7c73\u9897\u7c92\u7684\u6cbb\u7597\u65b9\u6cd5\uff08\u5982mRNA\u75ab\u82d7\uff09\u7684\u91cd\u8981\u6027\u548c\u666e\u53ca\u7a0b\u5ea6\u4e0d\u65ad\u589e\u52a0\uff0c\u7eb3\u7c73\u533b\u836f\u7684\u76f8\u5173\u6027\u6b63\u5728\u52a0\u901f\u3002\u4e3a\u4e86\u9ad8\u6548\u751f\u4ea7\u8fd9\u4e9b\u65b0\u578b\u533b\u7597\u6cbb\u7597\u65b9\u6cd5\uff0c\u5236\u836f\u884c\u4e1a\u4e0d\u5f97\u4e0d\u91cd\u65b0\u8bc4\u4f30\u8fc7\u65f6\u7684\u73b0\u6709\u5236\u9020\u6d41\u7a0b\uff0c\u503e\u5411\u4e8e\u91c7\u7528DIANT Pharma\u7b49\u521b\u65b0\u7684\u5c16\u7aef\u6280\u672f\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone  wp-image-227\" src=\"https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395eec9e484.png\" alt=\"\" width=\"705\" height=\"608\" srcset=\"https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395eec9e484.png 899w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395eec9e484-300x259.png 300w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395eec9e484-768x662.png 768w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395eec9e484-500x431.png 500w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395eec9e484-800x690.png 800w\" sizes=\"(max-width: 705px) 100vw, 705px\" \/><\/p>\n<p><strong>mRNA-LNP\u6280\u672f<\/strong><\/p>\n<p><strong><a href=\"https:\/\/www.bihec.com\/diantpharma\/tag\/%e8%84%82%e8%b4%a8%e7%ba%b3%e7%b1%b3%e9%a2%97%e7%b2%92\/\" title=\"View all posts in \u8102\u8d28\u7eb3\u7c73\u9897\u7c92\" target=\"_blank\">\u8102\u8d28\u7eb3\u7c73\u9897\u7c92<\/a><\/strong>\uff08<a href=\"https:\/\/www.bihec.com\/diantpharma\/tag\/lnps\/\" title=\"View all posts in LNPs\" target=\"_blank\">LNPs<\/a>\uff09\u5df2\u6210\u4e3a\u7eb3\u7c73\u533b\u836f\u7684\u9996\u9009\u4f20\u9012\u6280\u672f\u3002\u5b83\u4eec\u4e3a\u65b0\u4e00\u4ee3\u65e5\u76ca\u590d\u6742\u7684\u6cbb\u7597\u836f\u7269\u3001\u75ab\u82d7\u548c\u80bf\u7624\u6cbb\u7597\u63d0\u4f9b\u4e86\u5fc5\u8981\u7684\u7597\u6548\u548c\u751f\u4ea7\u6548\u7387\u3002<\/p>\n<p>\u8fc7\u53bb\u5341\u5e74\u4e2d\uff0c\u57fa\u4e8eLNP\u7684\u4fe1\u4f7fRNA\uff08mRNA\uff09\u75ab\u82d7\u7684\u8fdb\u6b65\u6539\u53d8\u4e86\u514d\u75ab\u5b66\u7684\u9762\u8c8c\uff0c\u9884\u793a\u7740\u751f\u7269\u533b\u836f\u5236\u9020\u7684\u65b0\u65f6\u4ee3\u7684\u6765\u4e34\u3002\u50cfmRNA\u75ab\u82d7\u8fd9\u6837\u7684LNP\u6cbb\u7597\u836f\u7269\u4e0e\u4f20\u7edf\u836f\u7269\u76f8\u6bd4\u8868\u73b0\u51fa\u8f83\u9ad8\u7684\u7597\u6548\uff0c\u4f46\u9700\u8981\u73b0\u4ee3\u5316\u7684\u5236\u9020\u65b9\u6cd5\uff0c\u4ee5\u4fbf\u5728\u89c4\u6a21\u5316\u751f\u4ea7\u65f6\u5177\u6709\u6210\u672c\u6548\u76ca\u3002<\/p>\n<p>\u968f\u7740\u8d8a\u6765\u8d8a\u591a\u57fa\u4e8emRNA\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u5305\u62ec\u57fa\u56e0\u7f16\u8f91\u7684\u6cbb\u7597\u65b9\u6cd5\u5728\u4e34\u5e8a\u8bd5\u9a8c\u548c\u5e02\u573a\u4e0a\u4e0d\u65ad\u589e\u52a0\uff0c\u66f4\u65b0\u8fd9\u4e9b\u751f\u4ea7\u6a21\u5f0f\u53d8\u5f97\u6bd4\u4ee5\u5f80\u4efb\u4f55\u65f6\u5019\u90fd\u66f4\u52a0\u7d27\u8feb\u3002\u836f\u7269\u590d\u6742\u6027\u7684\u589e\u52a0\u9700\u8981\u65b0\u6280\u672f\uff0c\u80fd\u591f\u6210\u529f\u5730\u5305\u88f9\u6d3b\u6027\u836f\u7269\u6210\u5206\uff08APIs\uff09\u4ee5\u652f\u6301\u7597\u6548\u3002<\/p>\n<p>\u5f53\u7ed3\u5408\u8fc7\u7a0b\u5206\u6790\u6280\u672f\uff08PAT\uff09\u6765\u63a7\u5236\u5236\u9020\u8fc7\u7a0b\u4e2d\u7684\u7c92\u5f84\u548c\u5176\u4ed6\u5206\u6790\u53c2\u6570\u65f6\uff0c\u50cf<a href=\"https:\/\/www.bihec.com\/diantpharma\/tag\/diant-jet\/\" title=\"View all posts in DIANT Jet\" target=\"_blank\">DIANT Jet<\/a>\u8fd9\u6837\u7684\u6280\u672f\u53ef\u4ee5\u52a0\u5feb\u7eb3\u7c73\u533b\u836f\u7684\u751f\u4ea7\u901f\u5ea6\uff0c\u540c\u65f6\u6700\u5927\u9650\u5ea6\u5730\u51cf\u5c11\u8001\u5f0f\u6279\u5904\u7406\u751f\u7269\u5236\u9020\u4e2d\u56fa\u6709\u7684\u98ce\u9669\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone  wp-image-223\" src=\"https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395bf06cdf6.png\" alt=\"\" width=\"705\" height=\"495\" srcset=\"https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395bf06cdf6.png 975w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395bf06cdf6-300x211.png 300w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395bf06cdf6-768x540.png 768w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395bf06cdf6-500x351.png 500w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68395bf06cdf6-800x562.png 800w\" sizes=\"(max-width: 705px) 100vw, 705px\" \/><\/p>\n<p><strong>\u751f\u7269\u9776\u5411 <\/strong><\/p>\n<p>\u968f\u7740\u533b\u5b66\u53d8\u5f97\u8d8a\u6765\u8d8a\u4e13\u4e1a\u5316\uff0c\u5bf9\u9488\u5bf9\u4e2a\u4f53\u60a3\u8005\u548c\u7f55\u89c1\u75be\u75c5\u7684\u6cbb\u7597\u9700\u6c42\u4e0d\u65ad\u51fa\u73b0\uff0c\u8fd9\u4e9b\u6cbb\u7597\u65b9\u6cd5\u7684\u5de5\u4f5c\u673a\u5236\u81ea\u7136\u800c\u7136\u5730\u4e0d\u5f97\u4e0d\u53d1\u751f\u53d8\u5316\u3002\u8fd9\u5bfc\u81f4\u4e86\u5404\u79cd\u751f\u7269\u9776\u5411\u7eb3\u7c73\u9897\u7c92\u7684\u53d1\u5c55\uff0c\u7528\u4e8e\u8bca\u65ad\u6216\u6cbb\u7597\u5e38\u89c1\u548c\u590d\u6742\u75be\u75c5\u3002<\/p>\n<p>\u751f\u7269\u9776\u5411\u7eb3\u7c73\u533b\u836f\u662f\u901a\u8fc7\u9759\u8109\u6ce8\u5c04\u7684\u7eb3\u7c73\u9897\u7c92\uff0c\u4ee5\u6709\u9488\u5bf9\u6027\u7684\u65b9\u5f0f\u5c06\u836f\u7269\u6216\u6210\u50cf\u5242\u5206\u5e03\u5230\u4f53\u5185\u3002\u5b83\u4eec\u53ef\u4ee5\u9488\u5bf9\u7279\u5b9a\u5668\u5b98\u548c\u7ec4\u7ec7\uff0c\u4e00\u76f4\u5230\u7ec6\u80de\u548c\u4e9a\u7ec6\u80de\u533a\u3002<\/p>\n<p>\u8fd9\u4e9b\u836f\u7269\u5df2\u7ecf\u6210\u4e3a\u67d0\u4e9b\u764c\u75c7\u751a\u81f3\u8111\u635f\u4f24\u7684\u6709\u5e0c\u671b\u7684\u8bca\u65ad\u548c\u6cbb\u7597\u65b9\u6cd5\u3002\u5f88\u660e\u663e\uff0c\u57fa\u4e8e\u6db2\u4f53\u836f\u7269\u6709\u9488\u5bf9\u6027\u6295\u653e\u7684\u836f\u7269\u7684\u672a\u6765\u662f\u5149\u660e\u7684\uff0c\u957f\u6548\u9776\u5411\u6ce8\u5c04\u5242\u4e5f\u5373\u5c06\u95ee\u4e16\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone  wp-image-233\" src=\"https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68396504e0771.png\" alt=\"\" width=\"712\" height=\"565\" srcset=\"https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68396504e0771.png 869w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68396504e0771-300x238.png 300w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68396504e0771-768x610.png 768w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68396504e0771-500x397.png 500w, https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/img_68396504e0771-800x635.png 800w\" sizes=\"(max-width: 712px) 100vw, 712px\" \/><\/p>\n<p><strong>\u7c92\u5b50\u5de5\u7a0b<\/strong><\/p>\n<p>\u7c92\u5b50\u5de5\u7a0b\u662f\u751f\u7269\u5236\u836f\u5236\u9020\u4e2d\u7684\u4e00\u4e2a\u91cd\u8981\u9886\u57df\uff0c\u968f\u7740\u751f\u7269\u9776\u5411\u7eb3\u7c73\u533b\u836f\u7684\u51fa\u73b0\uff0c\u5bf9cGMP\u751f\u7269\u5236\u836f\u5236\u9020\u7684\u53d8\u5316\u4e5f\u4f34\u968f\u800c\u6765\uff0c\u5305\u62ec\u7c92\u5b50\u5de5\u7a0b\u7684\u53d1\u5c55\u3002<\/p>\n<p>\u4e3a\u4e86\u5f00\u53d1\u6709\u6548\u7684\u975e\u4fb5\u5165\u6027\u6cbb\u7597\u548c\u8bca\u65ad\u65b9\u6cd5\uff0c\u9700\u8981\u63a7\u5236\u7eb3\u7c73\u9897\u7c92\u7684\u591a\u4e2a\u5c5e\u6027\u3002\u7eb3\u7c73\u9897\u7c92\u7684\u5927\u5c0f\u3001\u5f62\u72b6\u3001\u5316\u5b66\u6027\u8d28\u3001\u8868\u9762\u6027\u8d28\u548c\u7ed3\u6784\u7b49\u5c5e\u6027\u51b3\u5b9a\u4e86\u5b83\u4eec\u7684\u751f\u7269\u5229\u7528\u5ea6\u3001\u6cbb\u7597\u6f5c\u529b\uff0c\u6700\u7ec8\u5f71\u54cd\u5b83\u4eec\u5728\u836f\u7269\u548c\u5176\u4ed6\u5e94\u7528\u4e2d\u7684\u8868\u73b0\u3002\u901a\u8fc7\u7c92\u5b50\u5de5\u7a0b\uff0c\u53ef\u4ee5\u8c03\u63a7\u8fd9\u4e9b\u5c5e\u6027\uff0c\u4ee5\u5b9e\u73b0\u66f4\u597d\u7684\u836f\u7269\u6548\u679c\u548c\u5e94\u7528\u6548\u679c\u3002<\/p>\n<p>\u5728\u5de5\u7a0b\u7eb3\u7c73\u9897\u7c92\uff08ENPs\uff09\u4e2d\u63a7\u5236\u8fd9\u4e9b\u5c5e\u6027\uff0c\u5df2\u7ecf\u6210\u4e3a\u5236\u836f\u5236\u9020\u4e2d\u7684\u4e00\u4e2a\u91cd\u8981\u4f18\u5148\u4e8b\u9879\uff0c\u4ee5\u786e\u4fdd\u8fd9\u4e9b\u65b0\u578b\u7eb3\u7c73\u533b\u836f\u548c\u5176\u4ed6\u7eb3\u7c73\u9897\u7c92\u4ea7\u54c1\u7684\u8d28\u91cf\u548c\u7597\u6548\u3002<\/p>\n<p>\u95ed\u73af\u7cfb\u7edf\u7eb3\u7c73\u9897\u7c92\u5236\u9020\u7684\u5e94\u7528\uff0c\u6bd4\u5982DIANT\u7684\u4e13\u6709\u5de5\u827a\uff0c\u5df2\u7ecf\u88ab\u8bc1\u660e\u5728\u7ba1\u7406\u8fd9\u4e9b\u5c5e\u6027\u65b9\u9762\u8d77\u5230\u4e86\u5f88\u5927\u7684\u5e2e\u52a9\uff0c\u901a\u8fc7\u81ea\u52a8\u63a7\u5236\u7c92\u5f84\u5927\u5c0f\u5e76\u9650\u5236\u5728\u5236\u9020\u8fc7\u7a0b\u4e2d\u4eba\u4e3a\u5e72\u9884\u7684\u5fc5\u8981\u6027\u3002\u8fd9\u79cd\u6280\u672f\u6709\u52a9\u4e8e\u786e\u4fdd\u751f\u4ea7\u7684\u7eb3\u7c73\u9897\u7c92\u5177\u6709\u4e00\u81f4\u7684\u8d28\u91cf\u548c\u6027\u80fd\uff0c\u4ece\u800c\u63d0\u9ad8\u7eb3\u7c73\u533b\u836f\u548c\u5176\u4ed6\u7eb3\u7c73\u9897\u7c92\u4ea7\u54c1\u7684\u751f\u4ea7\u6548\u7387\u548c\u53ef\u9760\u6027\u3002<\/p>\n<p><a href=\"https:\/\/www.bihec.com\/diantpharma\/wp-content\/uploads\/sites\/2274\/2025\/05\/LARU-Discovery\u7eb3\u7c73\u9897\u7c92\u7814\u7a76\u5904\u7406\u7cfb\u7edf-V1.pdf\">LARU Discovery\u7eb3\u7c73\u9897\u7c92\u7814\u7a76\u5904\u7406\u7cfb\u7edf V1<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<br><div class=\"tagcloud\"><a href=\"https:\/\/www.bihec.com\/diantpharma\/tag\/diant-jet\/\" class=\"tag-cloud-link tag-link-0 tag-link-position-1\" style=\"font-size: 8pt;\" aria-label=\"DIANT Jet (1\u4e2a\u9879\u76ee)\">DIANT Jet<\/a>\n<a href=\"https:\/\/www.bihec.com\/diantpharma\/tag\/diant-laru-%e5%ae%9e%e9%aa%8c%e5%ae%a4%e7%ba%b3%e7%b1%b3%e9%a2%97%e7%b2%92%e5%90%88%e6%88%90%e7%b3%bb%e7%bb%9f\/\" class=\"tag-cloud-link tag-link-1 tag-link-position-2\" style=\"font-size: 18.5pt;\" aria-label=\"Diant LARU \u5b9e\u9a8c\u5ba4\u7eb3\u7c73\u9897\u7c92\u5408\u6210\u7cfb\u7edf (3\u4e2a\u9879\u76ee)\">Diant LARU \u5b9e\u9a8c\u5ba4\u7eb3\u7c73\u9897\u7c92\u5408\u6210\u7cfb\u7edf<\/a>\n<a 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